Peptide
Reference library
Educational peptide reference — research use only.
Research & educational use only
For laboratory and educational research only. Not for human or veterinary consumption. This is not medical advice. Always follow applicable laws and consult qualified professionals.
The calculator performs unit math for research reference. It must not be used to plan or guide dosing in humans or animals. Verify all figures independently in your lab protocol.
Cerebrolysin
A neuropeptide mixture studied in stroke recovery and neurodegeneration research.
- Half-life (approx.)
- ~1–2 h (approx., after IM)
- Diluent
- Supplied in solution — do not reconstitute
- Common vials
- 215 mg
Half-life figures are literature approximations for educational reference — not pharmacokinetic advice.
Overview
Cerebrolysin is a porcine brain-derived peptide mixture used in stroke-recovery and neurodegeneration research, especially in European and Asian trial literature. It contains low-molecular-weight neuropeptides thought to mimic endogenous neurotrophic signaling. Porcine brain peptide mixture approved in some countries for stroke and dementia adjunct research.
Structure & identity
Porcine brain peptide mixture (low MW neuropeptides)
- Sequence / structure
- Porcine brain peptide mixture (low MW neuropeptides)
Status: Approved in some countries; not FDA-approved in the US.
Mechanism
Approved in some countries; not FDA-approved in the US.
Neuropeptide mixture mimics endogenous neurotrophic factor profiles post-ischemic injury. Low-MW neuropeptide profile intended to mimic post-ischemic neurotrophic milieu.
Studies & clinical programs
Post-stroke recovery trials
Published research models
- Peer-reviewed literature documents endpoints under Post-stroke recovery trials experimental designs.
Alzheimer's disease adjunct research
Published research models
- Peer-reviewed literature documents endpoints under Alzheimer's disease adjunct research experimental designs.
Research models in literature
- Post-stroke recovery trials
- Alzheimer's disease adjunct research
Literature highlights
- Porcine neuropeptide mixture studied in post-stroke and traumatic brain injury trials.
- Cognitive and functional recovery endpoints compared with standard care in some jurisdictions.
- Low-molecular-weight peptide profile mimics endogenous neurotrophic factor signatures.
Key targets & pathways
Research areas
Routes in research literature
Also known as
Stability & storage phases
| Phase | Condition | Guidance |
|---|---|---|
| Lyophilized | Refrigerated (2–8 °C); do not shake vial | Recombinant proteins and glycoproteins require gentle handling; inspect cake integrity and store upright per IU potency literature. |
| Reconstituted | Manufacturer diluent or bacteriostatic water, refrigerated | Swirl gently until dissolved — never shake vigorously; refrigerated stability is often shorter than small peptides (days to ~2 weeks). |
| Working aliquots | Frozen (−20 °C) in protein-grade tubes | Aliquot by IU or mg immediately after reconstitution; label concentration and avoid foam formation during draw. |
Stability windows are formulation-dependent — verify published data and your lab SOP.
Reconstitution reference table
| Vial (mg) | Diluent (mL) | mcg/mL | Units @ 100 mcg | Units @ 250 mcg | Units @ 500 mcg |
|---|---|---|---|---|---|
| 215 | 5 | 43000.0 | 0.2 | 0.6 | 1.2 |
U-100 insulin syringe scale (100 units = 1 mL). Illustrative only — not dosing guidance.
Reconstitution steps
- Allow vial to reach room temperature (15–30 min)
- Swab rubber stopper with alcohol prep pad
- Draw calculated bacteriostatic water into syringe
- Inject diluent slowly down vial wall — do not spray directly onto cake
- Gently swirl until fully dissolved — do not shake vigorously
- Label with date, concentration, and diluent volume
- Refrigerate and use within your lab stability window
Supplied in various ampoule sizes; follow published research protocol.
Laboratory record checklist
- Compound identity recorded in lab notebook (name, lot, preparation date)
- Analytical identity cross-checked against published sequence or structure
- Potency or concentration documented from analytical certificate when available
- Purity or HPLC data filed when provided with research material
- Appearance noted: intact lyophilized cake or uniform powder
- Sterility / endotoxin report archived when available
- Storage temperature applied immediately per published stability guidance