Peptide
Reference library
Educational peptide reference — research use only.
Research & educational use only
For laboratory and educational research only. Not for human or veterinary consumption. This is not medical advice. Always follow applicable laws and consult qualified professionals.
The calculator performs unit math for research reference. It must not be used to plan or guide dosing in humans or animals. Verify all figures independently in your lab protocol.
Selank
A synthetic analog of tuftsin studied in anxiety and cognition research.
- Half-life (approx.)
- ~minutes (approx., rapid); amidate forms longer
- Diluent
- Bacteriostatic water (0.9% benzyl alcohol)
- Common vials
- 5, 10 mg
Half-life figures are literature approximations for educational reference — not pharmacokinetic advice.
Overview
Selank is a synthetic tuftsin analog with anxiolytic and nootropic claims studied in Russian clinical literature without sedation in animal models. Mechanistic work examines GABA modulation, enkephalin stabilization, and BDNF expression. Tuftsin-derived anxiolytic peptide with prominent intranasal research literature.
Structure & identity
Heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro + stabilizing modifications
- Sequence / structure
- Heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro + stabilizing modifications
Mechanism
Tuftsin analog modulating GABAergic transmission and enkephalinase inhibition. GABAergic modulation and enkephalinase inhibition contribute to anxiolytic behavioral endpoints.
Studies & clinical programs
Elevated plus maze anxiety
Published research models
- Peer-reviewed literature documents endpoints under Elevated plus maze anxiety experimental designs.
GABAergic binding assays
Published research models
- Peer-reviewed literature documents endpoints under GABAergic binding assays experimental designs.
Research models in literature
- Elevated plus maze anxiety
- GABAergic binding assays
Literature highlights
- Tuftsin analog modulates GABAergic transmission in elevated plus maze anxiety models.
- Enkephalinase inhibition and immune-modulation assays supplement anxiolytic research.
- Intranasal delivery prominent in Russian peptide neuropharmacology literature.
Combination research notes
Semax + Selank mix documented in literature; intranasal research common.
Key targets & pathways
Research areas
Routes in research literature
Also known as
Handling cautions
- Intranasal research forms common
Stability & storage phases
| Phase | Condition | Guidance |
|---|---|---|
| Lyophilized | Refrigerated (2–8 °C), sealed | Research peptide powder for nasal formulations should remain cold and dry until reconstitution; amidate forms may have distinct published stability guidance. |
| Reconstituted (nasal solution) | Sterile water or bacteriostatic water, refrigerated | Nasal research solutions are often prepared at lower concentrations; use within published stability windows (commonly 1–2 weeks refrigerated). |
| Working aliquots | Single-use nasal sprayer fills or frozen micro-aliquots | Avoid contamination of multi-use bottles in lab settings; sterile technique and cold chain reduce protease and microbial risk. |
Stability windows are formulation-dependent — verify published data and your lab SOP.
Reconstitution reference table
| Vial (mg) | Diluent (mL) | mcg/mL | Units @ 100 mcg | Units @ 250 mcg | Units @ 500 mcg |
|---|---|---|---|---|---|
| 5 | 2 | 2500.0 | 4 | 10 | 20 |
| 10 | 2 | 5000.0 | 2 | 5 | 10 |
U-100 insulin syringe scale (100 units = 1 mL). Illustrative only — not dosing guidance.
Reconstitution steps
- Allow vial to reach room temperature (15–30 min)
- Swab rubber stopper with alcohol prep pad
- Draw calculated bacteriostatic water into syringe
- Inject diluent slowly down vial wall — do not spray directly onto cake
- Gently swirl until fully dissolved — do not shake vigorously
- Label with date, concentration, and diluent volume
- Refrigerate and use within your lab stability window
Reconstituted per research protocol; intranasal forms differ.
Laboratory record checklist
- Compound identity recorded in lab notebook (name, lot, preparation date)
- Analytical identity cross-checked against published sequence or structure
- Potency or concentration documented from analytical certificate when available
- Purity or HPLC data filed when provided with research material
- Appearance noted: intact lyophilized cake or uniform powder
- Sterility / endotoxin report archived when available
- Storage temperature applied immediately per published stability guidance