Peptide
Reference library
Educational peptide reference — research use only.
Research & educational use only
For laboratory and educational research only. Not for human or veterinary consumption. This is not medical advice. Always follow applicable laws and consult qualified professionals.
The calculator performs unit math for research reference. It must not be used to plan or guide dosing in humans or animals. Verify all figures independently in your lab protocol.
HMG
A gonadotropin mixture studied in fertility and ovarian-stimulation research.
- Half-life (approx.)
- ~24–36 h (approx.)
- Diluent
- Bacteriostatic water (0.9% benzyl alcohol)
- Common vials
- 75, 150 mg
Half-life figures are literature approximations for educational reference — not pharmacokinetic advice.
Overview
HMG (human menopausal gonadotropin) combines FSH and LH activity for ovarian-stimulation research in assisted-reproduction protocols. Dosing is IU-based; material is typically lyophilized with potency stated per vial. Urinary-derived FSH/LH mixture for follicular development research — IU potency on label.
Structure & identity
Urinary FSH/LH glycoprotein mixture
- Sequence / structure
- Urinary FSH/LH glycoprotein mixture
Status: Clinical fertility research — IU potency labeling.
Mechanism
Clinical fertility research — IU potency labeling.
Combined FSH and LH activity from urinary gonadotropins for follicular development research. Combined gonadotropin activity supports multi-follicular recruitment in IVF models.
Studies & clinical programs
Controlled ovarian hyperstimulation
Published research models
- Peer-reviewed literature documents endpoints under Controlled ovarian hyperstimulation experimental designs.
Anovulation research
Published research models
- Peer-reviewed literature documents endpoints under Anovulation research experimental designs.
Research models in literature
- Controlled ovarian hyperstimulation
- Anovulation research
Literature highlights
- Urinary FSH/LH gonadotropin mixture used in controlled ovarian hyperstimulation research.
- Follicular development endpoints monitored via ultrasound and estradiol panels.
- IU potency labeling required — distinct from mg-based peptide reconstitution math.
Combination research notes
Controlled ovarian hyperstimulation research pairs hMG with hCG trigger protocols.
Key targets & pathways
Research areas
Routes in research literature
Also known as
Handling cautions
- IU-based potency on label
Stability & storage phases
| Phase | Condition | Guidance |
|---|---|---|
| Lyophilized | Refrigerated (2–8 °C); do not shake vial | Recombinant proteins and glycoproteins require gentle handling; inspect cake integrity and store upright per IU potency literature. |
| Reconstituted | Manufacturer diluent or bacteriostatic water, refrigerated | Swirl gently until dissolved — never shake vigorously; refrigerated stability is often shorter than small peptides (days to ~2 weeks). |
| Working aliquots | Frozen (−20 °C) in protein-grade tubes | Aliquot by IU or mg immediately after reconstitution; label concentration and avoid foam formation during draw. |
Stability windows are formulation-dependent — verify published data and your lab SOP.
Reconstitution reference table
| Vial (mg) | Diluent (mL) | mcg/mL | Units @ 100 mcg | Units @ 250 mcg | Units @ 500 mcg |
|---|---|---|---|---|---|
| 75 | 1 | 75000.0 | 0.1 | 0.3 | 0.7 |
| 150 | 1 | 150000.0 | 0.1 | 0.2 | 0.3 |
U-100 insulin syringe scale (100 units = 1 mL). Illustrative only — not dosing guidance.
Reconstitution steps
- Allow vial to reach room temperature (15–30 min)
- Swab rubber stopper with alcohol prep pad
- Draw calculated bacteriostatic water into syringe
- Inject diluent slowly down vial wall — do not spray directly onto cake
- Gently swirl until fully dissolved — do not shake vigorously
- Label with date, concentration, and diluent volume
- Refrigerate and use within your lab stability window
IU-based; reconstitute per label and research protocol.
Laboratory record checklist
- Compound identity recorded in lab notebook (name, lot, preparation date)
- Analytical identity cross-checked against published sequence or structure
- Potency or concentration documented from analytical certificate when available
- Purity or HPLC data filed when provided with research material
- Appearance noted: intact lyophilized cake or uniform powder
- Sterility / endotoxin report archived when available
- Storage temperature applied immediately per published stability guidance