Peptide
Reference library
Educational peptide reference — research use only.
Research & educational use only
For laboratory and educational research only. Not for human or veterinary consumption. This is not medical advice. Always follow applicable laws and consult qualified professionals.
The calculator performs unit math for research reference. It must not be used to plan or guide dosing in humans or animals. Verify all figures independently in your lab protocol.
BPC-157
A synthetic peptide studied in preclinical models for tissue and gut research.
- Half-life (approx.)
- ~4 h (approx., rodent)
- Diluent
- Bacteriostatic water (0.9% benzyl alcohol)
- Common vials
- 5, 10 mg
Half-life figures are literature approximations for educational reference — not pharmacokinetic advice.
Overview
BPC-157 is a synthetic pentadecapeptide derived from gastric juice protein, widely studied in rodent models of tendon, ligament, and gut injury. Mechanistic work examines angiogenesis, nitric oxide pathways, and growth-factor upregulation in preclinical settings. Among the most referenced soft-tissue repair peptides in rodent tendon, ligament, and GI injury models.
Structure & identity
15-mer pentadecapeptide (Body Protection Compound sequence)
- Sequence / structure
- 15-amino-acid pentadecapeptide (Body Protection Compound)
Mechanism
BPC-157 modulates growth-factor signaling, nitric oxide pathways, and angiogenesis in tissue-injury preclinical models without published human therapeutic approval.
Upregulates growth-factor pathways, promotes angiogenesis, and modulates NO system in injury models. FAK-paxillin and VEGF pathway upregulation support angiogenesis at injury margins.
Studies & clinical programs
Tendon and ligament injury models
Rodent transection and crush models
- Accelerated healing markers in Achilles and quadriceps tendon studies.
- Angiogenesis and growth-factor pathway modulation reported in preclinical literature.
Gastrointestinal protection models
NSAID-induced gastric lesion and colitis rodents
- Mucosal healing and anti-inflammatory endpoints in GI injury models.
Research models in literature
- Rat tendon transection
- Colitis models
- NSAID gastric lesion models
Literature highlights
- Tendon transection and ligament injury models report angiogenesis and migration markers.
- Gastric lesion and colitis rodent studies examine NO-system and growth-factor modulation.
- One of the most cited peptides in soft-tissue repair preclinical literature.
Combination research notes
Commonly researched with TB-500 in recovery blends (BPC+TB mix, GLOW, KLOW).
Key targets & pathways
Research areas
Routes in research literature
Also known as
Handling cautions
- Stable in gastric acid — oral research forms exist
Stability & storage phases
| Phase | Condition | Guidance |
|---|---|---|
| Lyophilized | Sealed vial, refrigerated (2–8 °C) | Intact lyophilized cake or powder is typically stable for months to years per published stability data; protect from moisture, light, and repeated freeze-thaw of the dry vial. |
| Reconstituted | Bacteriostatic water (0.9% benzyl alcohol), refrigerated | Most aqueous peptide solutions remain usable for approximately 2–4 weeks refrigerated; verify published stability data and label with reconstitution date. |
| Working aliquots | Pre-drawn syringes or microtubes, frozen (−20 °C) | Aliquot promptly after mixing to limit freeze-thaw cycles on the main vial; thaw once and use to reduce protease-mediated degradation. |
Stability windows are formulation-dependent — verify published data and your lab SOP.
Reconstitution reference table
| Vial (mg) | Diluent (mL) | mcg/mL | Units @ 100 mcg | Units @ 250 mcg | Units @ 500 mcg |
|---|---|---|---|---|---|
| 5 | 2 | 2500.0 | 4 | 10 | 20 |
| 10 | 2 | 5000.0 | 2 | 5 | 10 |
U-100 insulin syringe scale (100 units = 1 mL). Illustrative only — not dosing guidance.
Reconstitution steps
- Allow vial to reach room temperature (15–30 min)
- Swab rubber stopper with alcohol prep pad
- Draw calculated bacteriostatic water into syringe
- Inject diluent slowly down vial wall — do not spray directly onto cake
- Gently swirl until fully dissolved — do not shake vigorously
- Label with date, concentration, and diluent volume
- Refrigerate and use within your lab stability window
Often reconstituted with 1–2 mL bacteriostatic water.
Laboratory record checklist
- Compound identity recorded in lab notebook (name, lot, preparation date)
- Analytical identity cross-checked against published sequence or structure
- Potency or concentration documented from analytical certificate when available
- Purity or HPLC data filed when provided with research material
- Appearance noted: intact lyophilized cake or uniform powder
- Sterility / endotoxin report archived when available
- Storage temperature applied immediately per published stability guidance