Peptide
Reference library
Educational peptide reference — research use only.
Research & educational use only
For laboratory and educational research only. Not for human or veterinary consumption. This is not medical advice. Always follow applicable laws and consult qualified professionals.
The calculator performs unit math for research reference. It must not be used to plan or guide dosing in humans or animals. Verify all figures independently in your lab protocol.
Ipamorelin
A growth-hormone-secretagogue peptide used in endocrine research.
- Half-life (approx.)
- ~2 h (approx., subQ)
- Diluent
- Bacteriostatic water (0.9% benzyl alcohol)
- Common vials
- 2, 5, 10 mg
Half-life figures are literature approximations for educational reference — not pharmacokinetic advice.
Overview
Ipamorelin is a selective GH secretagogue with minimal effect on cortisol and prolactin in most endocrine research models. Its clean receptor profile makes it a common reference compound in GH-axis combination studies. Most selective common GHRP — minimal cortisol/prolactin co-release in stimulation literature.
Structure & identity
Pentapeptide Aib-His-D-2-Nal-D-Phe-Lys
- Sequence / structure
- Pentapeptide Aib-His-D-2-Nal-D-Phe-Lys
Mechanism
Selective GHS-R1a agonist with minimal cortisol/prolactin elevation in most models. GHS-R1a agonism produces clean GH pulses suitable for dual-axis combination research.
Studies & clinical programs
GH pulse selectivity studies
Published research models
- Peer-reviewed literature documents endpoints under GH pulse selectivity studies experimental designs.
Cortisol/prolactin monitoring
Published research models
- Peer-reviewed literature documents endpoints under Cortisol/prolactin monitoring experimental designs.
Research models in literature
- GH pulse selectivity studies
- Cortisol/prolactin monitoring
Literature highlights
- Selective GHS-R1a agonist with minimal cortisol/prolactin elevation in most stimulation studies.
- Standard GHRP partner for GHRH analogs in dual-axis research blends.
- GH pulse selectivity compared with GHRP-2 and GHRP-6 in pituitary perfusion models.
Combination research notes
Paired with CJC-1295 no DAC or tesamorelin in blends.
Key targets & pathways
Research areas
Routes in research literature
Stability & storage phases
| Phase | Condition | Guidance |
|---|---|---|
| Lyophilized | Sealed vial, refrigerated (2–8 °C) | Intact lyophilized cake or powder is typically stable for months to years per published stability data; protect from moisture, light, and repeated freeze-thaw of the dry vial. |
| Reconstituted | Bacteriostatic water (0.9% benzyl alcohol), refrigerated | Most aqueous peptide solutions remain usable for approximately 2–4 weeks refrigerated; verify published stability data and label with reconstitution date. |
| Working aliquots | Pre-drawn syringes or microtubes, frozen (−20 °C) | Aliquot promptly after mixing to limit freeze-thaw cycles on the main vial; thaw once and use to reduce protease-mediated degradation. |
Stability windows are formulation-dependent — verify published data and your lab SOP.
Reconstitution reference table
| Vial (mg) | Diluent (mL) | mcg/mL | Units @ 100 mcg | Units @ 250 mcg | Units @ 500 mcg |
|---|---|---|---|---|---|
| 2 | 2 | 1000.0 | 10 | 25 | 50 |
| 5 | 2 | 2500.0 | 4 | 10 | 20 |
| 10 | 2 | 5000.0 | 2 | 5 | 10 |
U-100 insulin syringe scale (100 units = 1 mL). Illustrative only — not dosing guidance.
Reconstitution steps
- Allow vial to reach room temperature (15–30 min)
- Swab rubber stopper with alcohol prep pad
- Draw calculated bacteriostatic water into syringe
- Inject diluent slowly down vial wall — do not spray directly onto cake
- Gently swirl until fully dissolved — do not shake vigorously
- Label with date, concentration, and diluent volume
- Refrigerate and use within your lab stability window
Typically reconstituted with 1–2 mL bacteriostatic water.
Laboratory record checklist
- Compound identity recorded in lab notebook (name, lot, preparation date)
- Analytical identity cross-checked against published sequence or structure
- Potency or concentration documented from analytical certificate when available
- Purity or HPLC data filed when provided with research material
- Appearance noted: intact lyophilized cake or uniform powder
- Sterility / endotoxin report archived when available
- Storage temperature applied immediately per published stability guidance